• Users Online: 1064
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2016  |  Volume : 43  |  Issue : 2  |  Page : 59-66

Measurement of serum trace elements levels in patients with juvenile idiopathic arthritis


1 Department of Rheumatology and Rehabilitation, Faculty of Medicine, Benha University, Benha, Egypt
2 Department of Biochemistry, Faculty of Medicine, Benha University, Benha, Egypt

Correspondence Address:
Nashwa I Hashaad
Department of Rheumatology and Rehabilitation, Faculty of Medicine, Benha University, Benha 13758
Egypt
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1110-161X.181875

Rights and Permissions

Aim This study was designed to assess the serum levels boron (B), copper (Cu), and zinc (Zn) in patients with juvenile idiopathic arthritis (JIA), and to evaluate their relationships with the disease activity parameters. Patients and methods This study was conducted on 30 children with JIA and 20 apparently healthy children. Patients were subjected to a thorough history-taking, clinical examination, plain radiography of both hands, and laboratory investigations including erythrocyte sedimentation rate, C-reactive protein, rheumatoid factor, and antinuclear antibodies. Disease activity was measured using the Juvenile arthritis disease activity score 27 (JADAS-27 score). Serum B, Cu, and Zn levels were also measured. Results The mean serum B level was highly statistically significantly lower in the JIA patients' group than that in the control group. The mean serum Cu level was highly statistically significantly higher in the JIA patients' group than that in the control group. Finally, the mean serum Zn level was statistically insignificantly lower in the JIA patients group than that in the control group. There were significant negative correlations between serum B concentrations and tender joint count (TJC). There were significant positive correlations between serum Cu concentrations and TJC, erythrocyte sedimentation rate, and JADAS-27. There were significant negative correlations between serum Zn concentrations and TJC and JADAS-27. Conclusion B serum level may play a role in the pathophysiology of JIA and its severity. Serum levels of B, Cu, and Zn seem to be of fundamental importance in the assessment of a JIA patient.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1335    
    Printed32    
    Emailed0    
    PDF Downloaded235    
    Comments [Add]    

Recommend this journal