|Year : 2019 | Volume
| Issue : 4 | Page : 278-284
MRI diagnosis in multiligamentous injuries of knee with associated dislocations and neurovasacular sequelae: a retrospective analysis of injury patterns
Reddy Ravikanth MD 1, Manu J Abraham2, Anoop Pilar2, Ashok Alapati2
1 Department of Radiology, Holy Family Hospital, Thodupuzha, India
2 Department of Orthopaedics, St John’s Medical College, Bangalore, India
|Date of Submission||12-Mar-2019|
|Date of Acceptance||17-Jul-2019|
|Date of Web Publication||01-Oct-2019|
Department of Radiology, Holy Family Hospital, Thodupuzha 685605
Source of Support: None, Conflict of Interest: None
Background Simultaneous injury of two or more knee ligaments with concurrent tears involving the anterior cruciate and medial collateral ligaments is considered to be associated with femorotibial knee dislocations (KD). The purpose of this study is to characterize multiligamentous knee injury patterns associated with dislocations on MRI and to describe the incidence of their sequelae such as tibial plateau fractures, peroneal nerve injuries, and posterolateral corner (PLC) injuries.
Participants and methods After obtaining institutional ethical committee approval, we retrospectively identified 108 multiligamentous knee injuries in 100 patients who met with trauma and were treated at our tertiary care center between April 2014 and December 2018. Descriptive statistics were reported using numbers and percentages for categorical variables in cases of multiligamentous injuries, ipsilateral tibial plateau fractures, ipsilateral femoral fractures, peroneal nerve injury, arterial injury, compartment syndrome, and PLC injuries.
Results The most common (39.8%) injury pattern was a combined disruption of the anterior cruciate ligament, posterior cruciate ligament, and PLC. Schenck KD III-M was the most common injury type in KD, constituting 16.7%. Medial-sided injuries were the most common injury patterns seen with KD. There was a significant risk of peroneal nerve injury with lateral-sided injuries.
Conclusion KD, though rare, may have devastating clinical sequelae such as compartment syndrome if not recognized and treated. Therefore, it is necessary to recognize imaging findings of femorotibial joint dislocations and associated injuries to the adjacent neurovascular bundles.
Keywords: anterior cruciate ligament, dislocation, femorotibial dislocation, knee MRI, multiligamentous injury, posterior cruciate ligament, posterolateral corner, posteromedial corner
|How to cite this article:|
Ravikanth R, Abraham MJ, Pilar A, Alapati A. MRI diagnosis in multiligamentous injuries of knee with associated dislocations and neurovasacular sequelae: a retrospective analysis of injury patterns. Egypt Rheumatol Rehabil 2019;46:278-84
|How to cite this URL:|
Ravikanth R, Abraham MJ, Pilar A, Alapati A. MRI diagnosis in multiligamentous injuries of knee with associated dislocations and neurovasacular sequelae: a retrospective analysis of injury patterns. Egypt Rheumatol Rehabil [serial online] 2019 [cited 2020 Sep 18];46:278-84. Available from: http://www.err.eg.net/text.asp?2019/46/4/278/268434
| Introduction|| |
Multiligamentous knee injuries are sometimes isolated but more often are the result of high-energy trauma and as such have various comorbidities ([Figure 1]). Recent reports have suggested that similar injury patterns are associated with vascular injury and peroneal nerve palsy in 19 and 20% of patients, respectively, and were done in small numbers of participants, which reported wide variations in the rates of associated injuries . Fractures in association with knee dislocations (KD) have been reported to be as high as 60% in patients with high-energy injuries, with 41% noted to have multiple fractures of the extremities . According to previous studies, the incidence of multiligamentous knee injuries ranges from 0.001 to 0.013% in all patients evaluated for orthopedic injuries . There is a surge in numbers from recent years, likely because of the improved survival of the critically injured trauma patient and the increased awareness of ligamentous injuries . Bicruciate ligament injuries have been reported to be equivalent to KD regarding frequency of major arterial injuries, the mechanism of injury, and severity of ligamentous injury. A missed diagnosis of KD can result in increased morbidity and risk of limb loss .
|Figure 1 Illustration demonstrating the knee anatomy. ACL, anterior cruciate ligament; LCL, lateral collateral ligament; MCL, medial collateral ligament; PCL, posterior cruciate ligament.|
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Anterior cruciate ligament
Approximately 70% of anterior cruciate ligament (ACL) injuries have a noncontact mechanism . The classic history of the noncontact injury involves a sudden deceleration, hyperextension, or twist, accompanied by a ‘pop’, significant pain, and subsequent swelling of the knee. The mechanism most commonly involves a valgus stress. This cascade of movements occurs when an athlete performs a straight-leg landing or a one-step stop with the knee hyperextended. ACL and posterior cruciate ligament (PCL) injuries rarely occur in isolation and are often associated with injuries to the secondary/supporting ligamentous structures that provide both static and dynamic stability against rotational forces.
Posterior cruciate ligament
The two most common mechanisms of PCL tear injury are forced hyperflexion and sustaining a posterior blow to the proximal tibia. Forced hyperflexion is the most common mechanism for an isolated PCL injury. During hyperflexion, the anterolateral component comes under increasing tension with knee flexion. The posteromedial component usually remains intact. A posterior blow to the proximal tibia of a flexed knee occurs with dashboard injuries to the knee during motor vehicle accidents causing to fall on a flexed knee. Hyperextension, most often is associated with a varus or valgus force, can also cause PCL injury.
Posterolateral corner injury
Posterolateral corner (PLC) injuries result in posterolateral rotational instability; they rarely occur in isolation . PLC injuries often occur in combination with cruciate ligament disruption, and they are most commonly associated with PCL injury ([Table 1]). Posterolateral instability is characterized by posterior subluxation and external rotation of the tibial plateau in relation to the femur. Therefore, a PCL injury necessitates careful scrutiny of the PLC structures on MRI. In the setting of trauma, PLC injury is most commonly caused by a direct blow at the anteromedial proximal tibia with a posterolateral force vector and knee in near full extension ([Table 2]). PLC injury is also seen with high-velocity trauma such as a complete KD. Bone marrow edema at the styloid process of the fibular head without fracture on MRI also warrants close investigation of the PLC structures for associated injury.
Posteromedial corner injury
The posteromedial corner (PMC) consists of ligamentous, meniscal, and myotendinous components that provide both static and dynamic constraint of anteromedial tibial rotation, in addition to secondary restraint of anterior tibial translation. The tendinous and ligamentous anatomy of the PMC, though complex, can be consistently identified on routine MRI. The PMC consists of the following structures: the oblique popliteal ligament, semimembranosus tendon, posteromedial capsule, posterior oblique ligament, deep components of the medial collateral ligament (MCL) complex, and the posterior horn of the medial meniscus ([Table 3]). PMC injuries occur most often during sports-related activities and are frequently overlooked, both clinically and at initial imaging, because they are often overshadowed by the more obvious cruciate and collateral ligamentous injuries. PMC injuries occur in combination with PCL injury, combined PCL and ACL injuries, ACL injury, MCL injury, and O’Donoghue’s triad of ACL, MCL, and medial meniscal injury.
Femorotibial joint dislocations
Kennedy  classified femorotibial joint dislocations based on the position of the tibia with respect to the femur. Anterior, posterior, medial, lateral, and rotary femorotibial dislocations may occur. Rotary femorotibial dislocations are further subdivided to include anteromedial, posteromedial, anterolateral, and posterolateral directions. Schenck et al. , classified KD by ligamentous involvement. French Society of Orthopedic Surgery and Traumatology Symposium in 2009  described a pathophysiologic approach to the classification, which covers the full range of complex ligamentous lesions occurring in KDs. As per this classification, there are two types of mechanism of injury, which can be evaluated through dynamic and static imaging. The first mechanism of injury, gaping, is a low-energy mechanism without weight bearing in the knee that results in ligament tear. The second mechanism of injury, translation, is a low-energy mechanism with weight bearing in the knee that results in ligamentous detachment. When only a single mechanism is involved, the lesion is classified as simple . Simple translation results in pure anterior or posterior dislocation, whereas simple gaping results in both cruciate ligament lesions . These mechanisms can also occur in combination during high-energy injuries and result in dislocation with peripheral tearing of ligaments.
Purpose of study
The purpose of this study is to characterize multiligamentous knee injury patterns associated with dislocations on MRI and to describe the incidence of their sequelae such as tibial plateau fractures, peroneal nerve injuries, and PLC injuries. We have described the mechanism of injury, ligamentous disruptions, and imaging findings of various types of KDs including injuries of the femorotibial, proximal tibiofibular, and patellofemoral joints. A step-by-step approach has been performed to evaluate the following: fractures and bone contusions − effusion and capsular disruption − cruciates − collaterals − menisci − extensor mechanism − posterior, lateral, and medial corner − cartilage − soft tissue. The MRI sequences the authors have used in such assessments were coronal and sagittal proton density, along with fat-suppressed sagittal and axial proton density/T2-weighted images.
| Participants and methods|| |
After obtaining institutional ethical committee approval, we retrospectively identified 108 multiligamentous knee injuries in 100 patients who were treated at our tertiary care center between April 2014 and December 2018.
In this study, the inclusion criteria were multiligamentous injuries to the ACL, PCL, or collateral ligaments and associated KDs on MRI, according to the classification of Schenck  (KD II, KD III, and KD IV; [Table 4]).
The exclusion criteria were severe intra-articular fractures of the ipsilateral knee and skeletal immaturity.
We verified multiligamentous injuries by MRI with clinical and surgical findings by fellowship-trained orthopedic specialists. All MRI studies were reviewed and confirmed by a senior radiologist. If discrepancies were noted, we took both MRI and surgical findings into consideration, acknowledging the fact that MRI does not necessarily differentiate between severe ligamentous sprain and discontinuity. MRI included T1-weighted and T2-weighted axial, coronal, and sagittal views and were evaluated for ligamentous injuries, fracture patterns, and associated KD when assessing ligamentous injury patterns. MRI studies were obtained and evaluated when examination findings suggested KDs or multiligamentous knee injury.
Data were obtained from the medical records of all 108 knees by using a predefined protocol that included orthopedic examinations, MRI findings, operative notes, and progress notes throughout the hospital course. Demographic information, arterial injuries, nerve injuries, associated fracture patterns, and KDs were recorded from initial evaluation.
Descriptive statistics were reported using numbers and percentages for categorical variables in cases of multiligamentous injuries, ipsilateral tibial plateau fractures, ipsilateral femoral fractures, peroneal nerve injury, arterial injury, compartment syndrome, and PLC injuries.
| Results|| |
A total of 108 multiligamentous knee injuries in 100 patients who met with trauma during the 4.5 years period were evaluated in our tertiary care center. The right knee was affected in 44 of the 100 study patients, the left knee was affected in 56, and bilateral knee injuries occurred in eight. Moreover, 70 patients were male and 30 were female. The average age of the patients was 32 years (range: 18–86 years). The most common (39.8%) injury pattern was a combined disruption of the ACL, PCL, and PLC ([Figure 2] and [Figure 3]). Overall, 30% of knees had associated ipsilateral tibial plateau fractures, and 20% had associated ipsilateral femoral fractures ([Figure 4] and [Figure 5]). Peroneal nerve injury occurred in 30% of knees, arterial injury in 20%, and compartment syndrome in 18%. The incidences of ligamentous injury based on MRI findings were as follows: ACL, 89.8% (97 of 108 extremities); PCL, 79.6% (86 of 108 extremities); PLC, 75.9% (82 extremities); and MCL, 26.8% (29 extremities). The noted injury patterns in multiligamentous knee injuries are shown in [Table 5]. The injury patterns associated with peroneal nerve injury are noted in [Table 6]. Peroneal nerve injuries were associated with PLC injuries in 87.5% of cases (28 of 32 knees). Further analysis of the specific injured structures showed that the lateral collateral ligament was involved 93.2% of the time (83 of 89 knees), the popliteus was involved 85.4% of the time (76 of 89 knees), and the biceps femoris was involved 35.9% of the time (32 of 89 knees). PLC injury patterns are shown in [Table 7]. Overall, 48% of patients presented with dislocated knees, which is consistent with previously reported rates of ∼50%. Injuries to the affected extremity are shown in [Table 8].
|Figure 2 Sagittal proton-density FS MRI of the knee joint in a case of multiligamentous injury in a 38-year-old woman, demonstrating complete tear of ACL (rightwards arrow) and PCL (leftwards arrow). ACL, anterior cruciate ligament; PCL, posterior cruciate ligament.|
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|Figure 3 Coronal proton-density FS MRI of the knee joint with trauma demonstrating grade 3 injury of MCL (lower leftwards arrow), partial thickness tear of LCL (upper leftwards arrow), and medial dislocation of femur (rightwards arrow). LCL, lateral collateral ligament; MCL, medial collateral ligament.|
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|Figure 4 Coronal T1-weighted MRI of knee joint demonstrating a Schatzker IV tibial plateau fracture with a depressed component (arrow).|
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|Figure 5 Coronal T1-weighted MRI of knee joint in a 71-year-old woman with trauma demonstrating intra-articular distal femoral fracture involving the medial condyle (arrow) with fracture line extending into the lateral condyle suggesting Hoffa fracture.|
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| Discussion|| |
Multiligamentous knee injuries are complex injuries that often require emergent treatment. Multiligamentous injuries have been defined as a complete cruciate tear (grade III) with a partial/complete tear of medial/lateral collateral (grade II/III) or a partial or complete tear of the other cruciate ligament (grade II or III). KDs remain the most common cause of multiligamentous injuries with various life-threatening and limb-threatening complications occurring with dislocation of the knee. Our findings suggest that multiligamentous knee injuries might be more prevalent than the 0.001–0.013%, as suggested in the literature .
The most important finding in this study was injuries with ACL, PCL, and PLC injuries being the commonest, constituting 39.8%, and Schenck KD III-M was the most common injury type in KDs, constituting 16.7%. The mean age at the time of injury was higher (38.5 years) than in previous studies. In our study, injuries with both cruciate ligaments torn and intact collaterals (KD II) were the least common (7.4%). Common peroneal nerve injuries were present in 29.6%, tibial plateau fractures in 29.6%, and vascular injuries in 20.3% of patients in this study. There were significantly greater odds for both common peroneal nerve injuries and popliteal artery injuries with lateral-sided injuries (KD III-L). Additionally, peroneal nerve injury was significantly associated with vascular injury. Medial-sided injuries were the most common injury patterns seen with KDs. There was a significant risk of peroneal nerve injury with lateral-sided injuries. PLC injuries commonly involved popliteus-lateral collateral ligament combination in 49.4% followed by popliteus-lateral collateral ligament-biceps femoris in 31.4%.
Johnson et al.  conducted a literature review of multiligamentous knee injuries in 2008 and found that up to 86% of KDs occur in male patients with a mean age between 30 and 32 years and that only 5% of patients present with bilateral injuries. These numbers are similar to our findings, with 70% male patients, ages averaging 32 years, and bilateral injuries present in only 8% of patients.
Robertson et al. , meta-analysis of previous KD studies, found that 41% of patients had ACL, PCL, and MCL injuries. Mechanisms of injury in our study were similar to those of the studies reviewed, and we found that the combined ACL–PCL–PLC injury pattern was the most prevalent (39.8%), with the ACL–PCL–MCL injury pattern accounting for only 16.7% of cases. PLC injuries might have an increased likelihood of being missed and might therefore have been underreported. PLC injuries had a high prevalence in our study and were noted in 75.9% of injured knees (82 of 108 knees) which is much higher than previously reported in the literature.
The peroneal nerve is susceptible to injury because of its relatively fixed position around the neck of the fibula. The incidence of peroneal nerve injuries occurring in association with KDs has been reported to be ∼20% . Our results found a higher incidence of peroneal nerve dysfunction at 30%. Similar to our findings, Niall et al. , in their review of 55 patients, found associated peroneal nerve injuries in 25% of patients with KDs. In this study, peroneal nerve injuries were associated with PLC injuries in 87.5% of cases (28 of 32 knees). Bottomley et al.  reported that 44% of KDs with avulsion fracture of the fibular head or soft-tissue avulsion from the fibular head had associated peroneal nerve damage. Our findings show that multiligamentous knee injuries are associated with fibular head fractures and bony avulsions 22% of the time (24 of 108 extremities).Fractures are common in association with multiligamentous knee injuries. Lustig et al. , in a prospective study of KDs and bicruciate knee injuries, found that 34% of patients had multiple fractures and 17% of the dislocations were associated with ipsilateral limb fracture. Overall, 25% (27/108) of the patients in our study sustained ipsilateral extremity fractures. Moreover, 29.6% of affected knees had ipsilateral tibial plateau fractures, and 20.3% had ipsilateral femoral fractures.
Initial trauma evaluation revealed that 48% of our patients presented with dislocated knees. This rate is consistent with previously reported rates of ∼50% . These injuries do not always present with gross deformity, which makes understanding their mechanism and injury patterns more important.
| Conclusion|| |
Multiligamentous knee injuries should be closely evaluated at presentation and during the hospital course as they serve as a marker of concomitant trauma to allow for early intervention for limb-threatening emergencies. KDs, though rare, may have devastating clinical sequelae such as compartment syndrome if not recognized and treated. Therefore it is necessary to recognize imaging findings of femorotibial joint dislocations and associated injuries to the adjacent neurovascular bundles.
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
| References|| |
Rihn JA, Groff YJ, Harner CD, Cha PS. The acutely dislocated knee: evaluation and management. J Am Acad Orthop Surg 2004; 12:334–346.
Becker EH, Watson JD, Dreese JC. Investigation of multiligamentous knee injury patterns with associated injuries presenting at a level I trauma center. J Orthop Trauma 2013; 27:226–231.
Zhang Y, Zhang X, Hao Y, Zhang YM, Wang M, Zhou Y et al.
Surgical management of the multiple-ligament injured knee: a case series from Chongqing, China and review of published reports. Orthop Surg 2013; 5:239–249.
Rochecongar G, Plaweski S, Azar M, Demey G, Arndt J, Louis ML et al.
French Society for Arthroscopy (Société française d’arthroscopie, SFA). Management of combined anterior or posterior cruciate ligament and posterolateral corner injuries: a systematic review. Orthop Traumatol Surg Res 2014; 100:S371–S378.
Twaddle BC, Bidwell TA, Chapman JR. Knee dislocations: where are the lesions? A prospective evaluation of surgical findings in 63 cases. J Orthop Trauma 2003; 17:198–202.
Cook S, Ridley TJ, McCarthy MA, Gao Y, Wolf BR, Amendola A et al.
Surgical treatment of multiligament knee injuries. Knee Surg Sports Traumatol Arthrosc 2015; 23:2983–2991.
Chahla J, Moatshe G, Dean CS, LaPrade RF. Posterolateral corner of the knee: current concepts. Arch Bone Jt Surg 2016; 4:97–103.
Kennedy JC. Complete dislocation of the knee joint. J Bone Joint Surg Am 1963; 45:889–904.
Schenck RC, Hunter RE, Ostrum RF, Perry CR. Knee dislocations. Instr Course Lect 1999; 48:515–522.
Boisgard S, Versier G, Descamps S, Lustig S, Trojani C, Rosset P et al.
Bicruciate ligament lesions and dislocation of the knee: mechanisms and classification. Orthop Traumatol Surg Res 2009; 95:627–631.
Ríos A, Villa A, Fahandezh H, de José C, Vaquero J. Results after treatment of traumatic knee dislocations. A report of 26 cases. J Trauma 2003; 55:489–494.
Sisto DJ, Warren RF. Complete knee dislocation. A follow-up study of operative treatment. Clin Orthop Relat Res 1985; 198:94–101.
Johnson ME, Foster L, DeLee JC. Neurologic and vascular injuries associated with knee ligament injuries. Am J Sports Med 2008; 36:2448–2462.
Robertson A, Nutton RW, Keating JF. Dislocation of the knee. J Bone Joint Surg Br 2006; 88:706–711.
Baltodano PA, Tong AJ, Chhabra A, Rosson GD. The role of magnetic resonance neurography in the postoperative management of peripheral nerve injuries. Neuroimaging Clin N Am 2014; 24:235–244.
Niall DM, Nutton RW, Keating JF. Palsy of the common peroneal nerve after traumatic dislocation of the knee. J Bone Joint Surg Br 2005; 87B:664–667.
Bottomley N, Williams A, Birch R, Noorani A, Lewis A, Lavelle J. Displacement of the common peroneal nerve in posterolateral corner injuries of the knee. J Bone Joint Surg Br 2005; 87:1225–1226.
Lustig S, Leray E, Boisrenoult P, Trojani C, Laffargue P, Saragaglia D et al.
Dislocation and bicruciate lesions of the knee. Epidemiology and acute stage assessment in a prospective series. Orthop Traumatol Surg Res 2009; 95:614–620.
Stannard JP, Bauer KL. Current concepts in knee dislocations: PCL, ACL, and medial sided injuries. J Knee Surg 2012; 25:287–294.
[Figure 1], [Figure 2], [Figure 3], [Figure 4], [Figure 5]
[Table 1], [Table 2], [Table 3], [Table 4], [Table 5], [Table 6], [Table 7], [Table 8]