Egyptian Rheumatology and Rehabilitation

CASE REPORT
Year
: 2015  |  Volume : 42  |  Issue : 3  |  Page : 159--161

Radiosynovectomy of ankle joint synovitis in juvenile rheumatoid arthritis treated with rhenium-188 tin colloid and imaging with SPECT/CT


Koramadai K Kamaleshwaran1, Thirumalaisamy S Gounder2, Boopathy Krishnan2, Madhav Mallia3, Radhakrishnan Kalarikal1, Ajit S Shinto1 
1 Department of Nuclear Medicine, PET/CT and Radionuclide Therapy, Comprehensive Cancer Care Center, Coimbatore, Tamil Nadu, India
2 Department of Orthopedics, Kovai Medical Center and Hospital Limited, Coimbatore, Tamil Nadu, India
3 Radiopharmaceuticals Chemistry Section (RPhCS), Bhabha Atomic Research Centre, Mumbai, India

Correspondence Address:
Koramadai K Kamaleshwaran
Department of Nuclear Medicine, PET/CT and Radionuclide Therapy, Comprehensive Cancer Care Center, Kovai Medical Center and Hospital Limited, Coimbatore - 641 014, Tamil Nadu
India

Rheumatoid arthritis is a chronic disease that is mainly characterized by asymmetric erosive synovitis, particularly affecting peripheral joints. Radiation synovectomy, or radiosynovectomy, was first described in 1950s as an adjuvant treatment for rheumatoid arthritis. Radiosynovectomy is based on the irradiation of the synovial joint by means of intra-articular administration of various b-emitting radiopharmaceuticals. As a generator-produced beta-emitting radionuclide, the importance of rhenium-188 (Re-188) in radionuclide therapy is increasing rapidly. There are previous studies that used Re-188 tin colloid in knee joint synovitis, but its use in ankle joint has not yet been reported. We describe the use of Re-188 tin colloid in a 19-year-old male patient who presented with ankle joint synovitis.


How to cite this article:
Kamaleshwaran KK, Gounder TS, Krishnan B, Mallia M, Kalarikal R, Shinto AS. Radiosynovectomy of ankle joint synovitis in juvenile rheumatoid arthritis treated with rhenium-188 tin colloid and imaging with SPECT/CT.Egypt Rheumatol Rehabil 2015;42:159-161


How to cite this URL:
Kamaleshwaran KK, Gounder TS, Krishnan B, Mallia M, Kalarikal R, Shinto AS. Radiosynovectomy of ankle joint synovitis in juvenile rheumatoid arthritis treated with rhenium-188 tin colloid and imaging with SPECT/CT. Egypt Rheumatol Rehabil [serial online] 2015 [cited 2020 Dec 5 ];42:159-161
Available from: http://www.err.eg.net/article.asp?issn=1110-161X;year=2015;volume=42;issue=3;spage=159;epage=161;aulast=Kamaleshwaran;type=0